![]() ![]() Despite both forms having distinct ways of administration, time of action and half-life duration, they have similar active components, being capable to produce psychostimulant effects (e.g., euphoria, energy gain, increased psychomotor activity and alertness, reduced appetite and sleep needs) in the user ( 5). ![]() Crack cocaine is produced with the same chemical base from cocaine, but with less amount of water, which results in a tropane alkaloid composition. ![]() Despite there is a few studies of epidemiological data on specific increase of crack consumption, Brazilian drugs reports have been estimated that 1.3% of drug users consume crack cocaine form annually ( 4). In South American countries, for example, crack cocaine “rocks”– a cocaine base obtained from hydrochloride conversion for smoking usually through a pipe ( 2)-has been widely consumed, such as in Brazil ( 3). Recent reports from Word Drug Report 2021 estimated a potential increase of 11% in global drug use for 2030, with pronounced impact in low- and middle income- countries, which could be, in part, explained by the availability of the drug in derived forms that provide greater returns to the drug market ( 1). Cocaine consumption has been increasing over the last decades. Cocaine Use Disorder (CUD) represents a serious public health problem with about 20 million people using the drug annually worldwide. ![]()
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